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Product Code: 11274
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Simenda 12.5 Injection ( levosimendan ) vial

Manufactured ByLUPIN LTD
ContainsLevosimendan
Description

Simenda 12.5 Injection is used in the treatment of acutely decompensated heart failure (ADHF) in patients who are not responding to conventional therapy. This medicine is not recommended for use in children below 18 years of age.

Side effects

Major & minor side effects for Simenda 12.5 Injection

  • Sleeplessness
     
  • Fast heartbeat
     
  • Low blood pressure
     
  • Nausea
     
  • Constipation
     
  • Diarrhea
     
  • Vomiting
     
  • Dizziness
     
  • Headache
     
  • Decreased potassium levels
     

Uses of Simenda 12.5 Injection

What is it prescribed for?

  • Acute Decompensated heart failure
    This medicine is used for the short-term treatment of the acutely decompensated chronic heart failure in patients who failed to respond to conventional therapy and in cases where the contractility of the heart is needed.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
     
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
     
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
     
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
     
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
     
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
     
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

 

Allergy

This medicine is not recommended for use in patients with a known allergy to Levosimendan or any other inactive ingredients present along with it.

Severe renal impairment

This medicine is not recommended for use in patients with severe kidney impairment due to the increased risk of worsening of the patient's condition.

Severe Hepatic impairment

This medicine is not recommended for use in patients with severe liver impairment due to the increased risk of worsening of the patient's condition.

Hypotension

This medicine is not recommended for use in patients with severe hypotension (low blood pressure) due to the increased risk of worsening of the patient's condition.

Tachycardia

This medicine is not recommended for use in patients with abnormal tachycardia (Increased heart rate) due to the increased risk of worsening of the patient's condition.

Torsades de Pointes

This medicine is not recommended for use in patients with Torsades de Pointes (a specific form of abnormal heart rhythm) due to the increased risk of worsening of the patient's condition.

Warnings for special population
 

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings
 

Kidney impairment

This medicine should be used with caution in patients with mild to moderately impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. This medicine is not recommended for use in patients with severe kidney impairment.

Liver impairment

This medicine should be used with caution in patients with mild to moderately impaired liver function due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. This medicine is not recommended for use in patients with severe liver impairment.

Monitoring

Regular monitoring of blood pressure, heart rate, ECG should be done during the treatment with this medicine and for 3 days after the end of infusion. In patients with mild to moderate liver or kidney impairment, the monitoring should be done for at least 5 days.

Use in children

This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.

Hypovolemia

This medicine is not recommended for use in patients with hypovolemia (low blood volume) due to the increased risk of worsening of the patient's condition. It should be corrected with appropriate measures before the initiating therapy with this medicine.

Hypokalemia

This medicine may lower the blood potassium levels and hence should be used with extreme caution in patients with hypokalemia (low blood potassium levels), since it may worsen the patient's condition. Therefore it is recommended to correct the low blood potassium levels with appropriate measures before the initiating therapy with this medicine. Close monitoring of blood potassium levels is necessary while receiving this medicine.

 

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
 
 

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
 

Intravenous Vasoactive Agents

 
Disease interactions
 

Disease

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