Medical Description: Phenadone Syrup

Phenadone Syrup is a combination medication containing dexamethasone, a corticosteroid with anti-inflammatory and immunosuppressive properties, and chlorpheniramine maleate, a first-generation antihistamine used to reduce allergic symptoms. This combination is used to help manage inflammatory and allergic conditions by decreasing immune-mediated responses and blocking histamine effects.

Active Ingredients

• Dexamethasone: 0.5 mg/5 mL
• Chlorpheniramine Maleate: 2 mg/5 mL

Therapeutic Indications
Phenadone may be prescribed for:

• Allergic rhinitis (hay fever)
• Skin allergies and itching
• Urticaria (hives)
• Hypersensitivity reactions
• Allergic respiratory symptoms
• Other inflammatory or allergic conditions as determined by a physician

Mechanism of Action
Dexamethasone

• Suppresses inflammatory mediators and reduces immune system activity.
• Helps reduce swelling, redness, and inflammation.

Chlorpheniramine Maleate

• Blocks histamine H1 receptors.
• Reduces symptoms such as sneezing, itching, watery eyes, and runny nose.

Common Adverse Effects
Potential side effects include:

• Drowsiness or sedation
• Dizziness
• Dry mouth
• Nausea
• Increased appetite
• Stomach discomfort
• Mood changes
• Restlessness

With prolonged or inappropriate corticosteroid use:

• Increased blood glucose
• Fluid retention
• Increased infection risk
• Adrenal suppression

Precautions

• May cause drowsiness; caution with driving or operating machinery.
• Use carefully in patients with diabetes, glaucoma, hypertension, or peptic ulcer disease.
• Long-term corticosteroid use should be monitored by healthcare professionals.
• Sudden discontinuation after prolonged use should be avoided.

Patient Disclaimer:
This information is provided for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Phenadone Syrup should be used only as prescribed by a qualified healthcare professional. Patients should consult their physician or pharmacist before starting, stopping, or changing any medication, particularly in children, pregnancy, breastfeeding, or individuals with chronic medical conditions.

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