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tadalafil20mg)      cialis 20mg 2 tablet)


1
Patient Information
CIALIS®
(See-AL-iss)
(tadalafil) tablets
Read this important information before you start taking CIALIS and each time you get a refill. There may be 
new information. You may also find it helpful to share this information with your partner. This information 
does not take the place of talking with your healthcare provider. You and your healthcare provider should talk 
about CIALIS when you start taking it and at regular checkups. If you do not understand the information, or 
have questions, talk with your healthcare provider or pharmacist.
What Is The Most Important Information I Should Know About CIALIS?
CIALIS can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain 
other medicines. You could get dizzy, faint, or have a heart attack or stroke.
Do not take CIALIS if you take any medicines called “nitrates.” Nitrates are commonly used to treat 
angina. Angina is a symptom of heart disease and can cause pain in your chest, jaw, or down your arm.
• Medicines called nitrates include nitroglycerin that is found in tablets, sprays, ointments, pastes, or 
patches. Nitrates can also be found in other medicines such as isosorbide dinitrate or isosorbide 
mononitrate. Some recreational drugs called “poppers” also contain nitrates, such as amyl nitrite and butyl 
nitrite.
• Ask your healthcare provider or pharmacist if you are not sure if any of your medicines are nitrates.
(See “Who Should Not Take CIALIS?”)
Tell all of your healthcare providers that you take CIALIS. If you need emergency medical care for a heart 
problem, it will be important for your healthcare provider to know when you last took CIALIS.
After taking a single tablet, some of the active ingredient of CIALIS remains in your body for more 
than 2 days. The active ingredient can remain longer if you have problems with your kidneys or liver, or you 
are taking certain other medications (see “Can Other Medicines Affect CIALIS?”).
Stop sexual activity and get medical help right away if you get symptoms such as chest pain, dizziness, or 
nausea during sex. Sexual activity can put an extra strain on your heart, especially if your heart is already weak 
from a heart attack or heart disease.
See also “What Are The Possible Side Effects Of CIALIS?”
What Is CIALIS?
CIALIS is a prescription medicine taken by mouth for the treatment of:
• men with erectile dysfunction (ED) 
• men with symptoms of benign prostatic hyperplasia (BPH) 
• men with both ED and BPH
CIALIS for the Treatment of ED
ED is a condition where the penis does not fill with enough blood to harden and expand when a man is 
sexually excited, or when he cannot keep an erection. A man who has trouble getting or keeping an erection 
should see his healthcare provider for help if the condition bothers him. CIALIS helps increase blood flow to 
the penis and may help men with ED get and keep an erection satisfactory for sexual activity. Once a man has 
completed sexual activity, blood flow to his penis decreases, and his erection goes away.
Some form of sexual stimulation is needed for an erection to happen with CIALIS.
CIALIS does not:
• cure ED2
• increase a man’s sexual desire
• protect a man or his partner from sexually transmitted diseases, including HIV. Speak to your healthcare 
provider about ways to guard against sexually transmitted diseases.
• serve as a male form of birth control
CIALIS is only for men over the age of 18, including men with diabetes or who have undergone 
prostatectomy.
CIALIS for the Treatment of Symptoms of BPH
BPH is a condition that happens in men, where the prostate gland enlarges which can cause urinary
symptoms.
CIALIS for the Treatment of ED and Symptoms of BPH
ED and symptoms of BPH may happen in the same person and at the same time. Men who have both ED and 
symptoms of BPH may take CIALIS for the treatment of both conditions.
CIALIS is not for women or children.
CIALIS must be used only under a healthcare provider’s care.
Who Should Not Take CIALIS?
Do not take CIALIS if you:
• take any medicines called “nitrates”.
• use recreational drugs called “poppers” like amyl nitrite and butyl nitrite. (See “What Is The Most 
Important Information I Should Know About CIALIS?”)
• are allergic to CIALIS or ADCIRCA®
, or any of its ingredients. See the end of this leaflet for a 
complete list of ingredients in CIALIS. Symptoms of an allergic reaction may include:
• rash
• hives
• swelling of the lips, tongue, or throat
• difficulty breathing or swallowing
Call your healthcare provider or get help right away if you have any of the symptoms of an allergic reaction 
listed above.
What Should I Tell My Healthcare Provider Before Taking CIALIS?
CIALIS is not right for everyone. Only your healthcare provider and you can decide if CIALIS is right 
for you. Before taking CIALIS, tell your healthcare provider about all your medical problems, including if you:
• have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask 
your healthcare provider if it is safe for you to have sexual activity. You should not take CIALIS if your 
healthcare provider has told you not to have sexual activity because of your health problems.
• have low blood pressure or have high blood pressure that is not controlled
• have had a stroke
• have liver problems
• have kidney problems or require dialysis
• have retinitis pigmentosa, a rare genetic (runs in families) eye disease
• have ever had severe vision loss, including a condition called NAION
• have stomach ulcers
• have a bleeding problem
• have a deformed penis shape or Peyronie’s disease
• have had an erection that lasted more than 4 hours
• have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia3
Can Other Medicines Affect CIALIS?
Tell your healthcare provider about all the medicines you take including prescription and non-prescription 
medicines, vitamins, and herbal supplements. CIALIS and other medicines may affect each other. Always check 
with your healthcare provider before starting or stopping any medicines. Especially tell your healthcare provider 
if you take any of the following*:
• medicines called nitrates (see “What Is The Most Important Information I Should Know About 
CIALIS?”)
• medicines called alpha blockers. These include Hytrin®
(terazosin HCl), Flomax®
(tamsulosin HCl), 
Cardura®
(doxazosin mesylate), Minipress®
(prazosin HCl), Uroxatral®
(alfuzosin HCl), Jalyn®
(dutasteride and tamsulosin HCl) or Rapaflo® (silodosin). Alpha-blockers are sometimes prescribed for 
prostate problems or high blood pressure. If CIALIS is taken with certain alpha blockers, your blood 
pressure could suddenly drop. You could get dizzy or faint.
• other medicines to treat high blood pressure (hypertension)
• medicines called HIV protease inhibitors, such as ritonavir (Norvir
®
, Kaletra®
)
• some types of oral antifungals such as ketoconazole (Nizoral®
), itraconazole (Sporanox®
)
• some types of antibiotics such as clarithromycin (Biaxin®
), telithromycin (Ketek®
), erythromycin (several 
brand names exist. Please consult your healthcare provider to determine if you are taking this medicine).
• other medicines or treatments for ED.
• CIALIS is also marketed as ADCIRCA for the treatment of pulmonary arterial hypertension. Do not take 
both CIALIS and ADCIRCA. Do not take sildenafil citrate (Revatio®
) with CIALIS.
How Should I Take CIALIS?
• Take CIALIS exactly as your healthcare provider prescribes it. Your healthcare provider will prescribe the 
dose that is right for you.
• Some men can only take a low dose of CIALIS or may have to take it less often, because of medical 
conditions or medicines they take.
• Do not change your dose or the way you take CIALIS without talking to your healthcare provider. Your 
healthcare provider may lower or raise your dose, depending on how your body reacts to CIALIS and your 
health condition.
• CIALIS may be taken with or without meals.
• If you take too much CIALIS, call your healthcare provider or emergency room right away.
How Should I Take CIALIS for Symptoms of BPH?
For symptoms of BPH, CIALIS is taken once daily.
• Do not take CIALIS more than one time each day.
• Take one CIALIS tablet every day at about the same time of day.
• If you miss a dose, you may take it when you remember but do not take more than one dose per day.
How Should I Take CIALIS for ED?
For ED, there are two ways to take CIALIS - either for use as needed OR for use once daily.
CIALIS for use as needed:
• Do not take CIALIS more than one time each day.
• Take one CIALIS tablet before you expect to have sexual activity. You may be able to have sexual 
activity at 30 minutes after taking CIALIS and up to 36 hours after taking it. You and your healthcare 
provider should consider this in deciding when you should take CIALIS before sexual activity. Some form
of sexual stimulation is needed for an erection to happen with CIALIS.4
• Your healthcare provider may change your dose of CIALIS depending on how you respond to the 
medicine, and on your health condition.
OR
CIALIS for once daily use is a lower dose you take every day.
• Do not take CIALIS more than one time each day.
• Take one CIALIS tablet every day at about the same time of day. You may attempt sexual activity at any
time between doses.
• If you miss a dose, you may take it when you remember but do not take more than one dose per day.
• Some form of sexual stimulation is needed for an erection to happen with CIALIS.
• Your healthcare provider may change your dose of CIALIS depending on how you respond to the 
medicine, and on your health condition.
How Should I Take CIALIS for Both ED and the Symptoms of BPH?
For both ED and the symptoms of BPH, CIALIS is taken once daily.
• Do not take CIALIS more than one time each day.
• Take one CIALIS tablet every day at about the same time of day. You may attempt sexual activity at any
time between doses.
• If you miss a dose, you may take it when you remember but do not take more than one dose per day.
• Some form of sexual stimulation is needed for an erection to happen with CIALIS.
What Should I Avoid While Taking CIALIS?
• Do not use other ED medicines or ED treatments while taking CIALIS.
• Do not drink too much alcohol when taking CIALIS (for example, 5 glasses of wine or 5 shots of 
whiskey). Drinking too much alcohol can increase your chances of getting a headache or getting dizzy, 
increasing your heart rate, or lowering your blood pressure.
What Are The Possible Side Effects Of CIALIS?
See “What Is The Most Important Information I Should Know About CIALIS?”
The most common side effects with CIALIS are: headache, indigestion, back pain, muscle aches, flushing, 
and stuffy or runny nose. These side effects usually go away after a few hours. Men who get back pain and 
muscle aches usually get it 12 to 24 hours after taking CIALIS. Back pain and muscle aches usually go away 
within 2 days.
Call your healthcare provider if you get any side effect that bothers you or one that does not go away.
Uncommon side effects include:
An erection that won’t go away (priapism). If you get an erection that lasts more than 4 hours, get medical 
help right away. Priapism must be treated as soon as possible or lasting damage can happen to your penis, 
including the inability to have erections.
Color vision changes, such as seeing a blue tinge (shade) to objects or having difficulty telling the difference 
between the colors blue and green.
In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including CIALIS) 
reported a sudden decrease or loss of vision in one or both eyes. It is not possible to determine whether these 
events are related directly to these medicines, to other factors such as high blood pressure or diabetes, or to a 
combination of these. If you experience sudden decrease or loss of vision, stop taking PDE5 inhibitors, 
including CIALIS, and call a healthcare provider right away.
Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been rarely reported 
in people taking PDE5 inhibitors, including CIALIS. It is not possible to determine whether these events are 5
related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of 
factors. If you experience these symptoms, stop taking CIALIS and contact a healthcare provider right away.
These are not all the possible side effects of CIALIS. For more information, ask your healthcare provider or 
pharmacist.
How Should I Store CIALIS?
Store CIALIS at room temperature between 59° and 86°F (15° and 30°C).
Keep CIALIS and all medicines out of the reach of children.
General Information About CIALIS:
Medicines are sometimes prescribed for conditions other than those described in patient information leaflets. 
Do not use CIALIS for a condition for which it was not prescribed. Do not give CIALIS to other people, even if 
they have the same symptoms that you have. It may harm them.
This is a summary of the most important information about CIALIS. If you would like more information, talk 
with your healthcare provider. You can ask your healthcare provider or pharmacist for information about 
CIALIS that is written for health providers. For more information you can also visit www.cialis.com, or call 
1-877-CIALIS1 (1-877-242-5471).
What Are The Ingredients In CIALIS?
Active Ingredient: tadalafil
Inactive Ingredients: croscarmellose sodium, hydroxypropyl cellulose, hypromellose, iron oxide, lactose 
monohydrate, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate, talc, titanium dioxide, and 
triacetin.
This Patient Information has been approved by the U.S. Food and Drug Administration
Rx only
CIALIS®
(tadalafil) is a registered trademark of Eli Lilly and Company.
*The brands listed are trademarks of their respective owners and are not trademarks of Eli Lilly and 
Company. The makers of these brands are not affiliated with and do not endorse Eli Lilly and Company or its 
products.
Revision Date October 2011
Marketed by: Lilly USA, LLC
Indianapolis, IN 46285, USA
www.cialis.com
Copyright © 2003, 2011, Eli Lilly and Company. All rights reserved.
PV 5227 AMP

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