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Brand: Bayer
Product Code: 11691
Availability: In Stock
Price: 29EGP
Ex Tax: 29EGP

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Proviron 25 mg ( mesterolone ) 20 tablets

WHAT PROVIRON IS USED FOR
Proviron is used to replace testosterone in men with hypogonadism. Male hypogonadism is a condition when the body does not produce enough testosterone.

Testosterone is a natural male hormone, known as an androgen, which controls normal sexual development in men.

Testosterone is essential for the development and maintenance of the male reproductive organs as well as other male characteristics, such as hair growth, deep voice, sexual drive, muscle mass and body fat distribution.

Proviron is for use in male patients only.

Ask your doctor if you have any questions about why this medicine has been prescribed for you.

Your doctor may have prescribed it for another reason.

BEFORE YOU USE PROVIRON
When you must not take it
Do not take Proviron if you have an allergy to:

mesterolone, the active ingredient in Proviron
any of the ingredients listed at the end of this leaflet.
Some of the symptoms of an allergic reaction may include:

shortness of breath
wheezing or difficulty breathing
swelling of the face, lips, tongue or other parts of the body
rash, itching or hives on the skin.
Do not take Proviron if you have:

prostate cancer
previous or existing liver tumours
male breast cancer
high blood calcium levels
Do not use this medicine after the expiry date printed on the pack and blister.

The expiry date is printed on the carton and on each blister after “EXP” (e.g. 11 18 refers to November 2018). The expiry date refers to the last day of that month. If it has expired return it to your pharmacist for disposal.

Do not use this medicine if the packaging is torn or shows signs of tampering.

If the packaging is damaged, return it to your pharmacist for disposal.

If you are not sure whether you should start taking this medicine, talk to your doctor.

Before you start to take it
Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes.

Before starting Proviron, your doctor will conduct an examination of your prostate. Your doctor will also note your medical history and perform other tests including a blood test.

Tell your doctor if you have or have had any of the following medical conditions:

prostate disease
liver disease
heart or blood vessel disease
high blood pressure
kidney disease
difficulty passing urine
migraines
epilepsy
diabetes
sleep apnoea (abnormal pauses in breathing during sleep)
polycythaemia (a blood disorder where too many red blood cells are being produced)
porphyria a rare metabolising disorder
If you have not told your doctor about any of the above, tell him/her before you start taking Proviron.

Use of androgens for reasons other than what your doctor prescribed carries a serious health risk and is strongly discouraged.

Use of Proviron during puberty can stunt your growth. Your doctor can discuss with you the risks and benefits involved.

Taking other medicines
Tell your doctor if you are taking any other medicines, including those that you buy without a prescription from your pharmacy, supermarket or health food shop.

Some medicines and Proviron may interfere with each other. These include:

phenobarbital or phenytoin, medicines used to treat seizures
cyclosporin, a medicine used to suppress the immune system
medicines used for diabetes
thyroxine, a medicine used to replace low thyroid levels
oral anticoagulants such as warfarin, ‘blood thinning’ medications to treat or prevent blood clots
neuromuscular blockers such as anaesthetics, medicines used to cause temporary paralysis
These medicines may be affected by Proviron or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines.

Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine.

HOW TO TAKE PROVIRON
Follow all directions given to you by your doctor or pharmacist carefully.

They may differ from the information contained in this leaflet.

If you do not understand the instructions printed on the pharmacist label, ask your doctor or pharmacist for help.

How much to take
Your doctor or pharmacist will tell you how much and how often you should take Proviron.

For Proviron to work best it is very important to take it exactly as your doctor tells you.

The usual treatment consists of 1-2 tablets three times per day. After a few months of treatment, your doctor may decrease the dose to 1 tablet two to three times a day.

Do not exceed the recommended dose your doctor has prescribed for you as this can increase your risk of side effects.

How to take it
Swallow the tablet whole with water.

When to take it
Take your medicine at about the same time each day

Taking it at the same time each day will have the best effect. It will also help you remember when to take it. It does not matter if you take this medicine before or after food.

How long to take it
Continue taking your medicine for as long as your doctor tells you. This medicine helps control your condition, but does not cure it. It is important to keep taking your medicine even if you feel well.

If you forget to take it
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.

Otherwise, take it as soon as you remember, and then go back to taking it as you would normally.

Do not take a double dose to make up for the dose that you missed.

If you are not sure what to do, ask your doctor or pharmacist.

If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.

If you take too much (overdose)
Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to the Accident and Emergency department at your nearest hospital, if you think you or anyone else may have taken too much Proviron. Do this even if there are no signs of discomfort or poisoning.

You may need urgent medical attention.

Excessive use of hormonal substances such as Proviron has been associated with liver abnormalities, tumours, changes to blood lipids, increased risk of heart disease, reduced glucose tolerance, decreased testosterone levels, enlargement of male breast tissue, stunted growth, psychiatric disturbances, acute withdrawal syndrome, vomiting blood or blood in stools and tendon damage.

WHILE YOU ARE TAKING PROVIRON
Things you must do

If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Proviron.

Tell any other doctors, dentists, and pharmacists who treat you that you are taking this medicine.

If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine.

It may affect other medicines used during surgery.

Keep all of your doctor’s appointments so that your progress can be checked.

Your doctor may do some tests (such as blood tests and regular examinations of the prostate) from time to time to make sure the medicine is working and to check for unwanted side effects.

If you experience prolonged stomach pain, blood in the stools or vomit, or yellowing of the skins and eyes during treatment with Proviron, tell your doctor immediately

There have been cases reported of patients developing liver tumours while taking Proviron. Your doctor may tell you to stop using Proviron.

Things you must not do
Do not take Proviron to treat any other complaints unless your doctor tells you to.

Do not give your Proviron tablets to anyone else, even if they have the same condition as you.

Do not stop taking your medicine or lower the dosage without checking with your doctor.

If you stop taking it suddenly, your condition may worsen or you may have unwanted side effects.

SIDE EFFECTS
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Proviron.

All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects.

Do not be alarmed by the following lists of possible side effects. You may not experience any of them.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor or pharmacist if you notice any of the following and they worry you:

headache
fluid retention
breast enlargement
increased sexual drive
psychiatric disturbances such as depression, aggression, increased or decreased energy levels, elation or irritability
acne
excessive hairiness
premature puberty
stunted growth
Tell your doctor immediately, or go to Accident and Emergency department at your nearest hospital if you notice any of the following:

symptoms of an enlarged prostate such as changes in urination, or blood in the urine or ejaculate
unwanted, frequent or prolonged and painful erections
severe stomach pain or tenderness which do not disappear within a short time
You may need urgent medical attention or hospitalisation.

Hormonal substances such as Proviron may quicken the growth of existing hormone dependent tissues and tumours If you are over 65 years of age, you may have an increased risk of developing prostatic hyperplasia (enlargement of the prostate) and prostatic cancer.

Tell your doctor or pharmacist if you notice anything that is making you feel unwell.

Other side effects not listed above may also occur in some people.

AFTER TAKING PROVIRON
Storage

Keep your tablets in the pack until it is time to take them.

If you take the tablets out of pack, they may not keep well.

Keep your tablets in a cool dry place where the temperature stays below 30°C.

Do not store it or any other medicine in the bathroom, near a sink, or on a window-sill.

Do not leave it in the car.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it.

A locked cupboard at least one-and-a half metres above the ground is a good place to store medicines.

Disposal
If your doctor tells you to stop taking Proviron or the tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.

Return any unused medicine to your pharmacist.

PRODUCT DESCRIPTION
What it looks like
Proviron tablets are round white scored tablets marked with “AX” inside a hexagon.

Each pack contains 50 tablets.

Ingredients
Active ingredient:

25 mg mesterolone per tablet

Inactive ingredients:

lactose
maize starch
povidone
methyl hydroxybenzoate
propyl hydroxybenzoate
magnesium stearate
Supplier
Made in Germany for:
Bayer Australia Ltd
ABN 22 000 138 714
875 Pacific Highway
Pymble NSW 2073

Australian Registration Number
Proviron (blister pack) - AUST R 136196
Proviron (bottle) - AUST R 10712

Date of preparation
November 2012

See TGA website (www.ebs.tga.gov.au) for latest Australian Consumer Medicine Information.

® Registered trademark of the Bayer Group, Germany

© Bayer Australia Ltd

All rights reserved

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