Medical Uses

Letrozole is an aromatase inhibitor used mainly to treat certain types of hormone-sensitive breast cancer in postmenopausal women. It may also be prescribed after other treatments such as tamoxifen to help reduce the risk of cancer recurrence.

How It Works?

Letrozole lowers estrogen levels in the body. Since some breast cancers grow in response to estrogen, reducing this hormone may help slow or stop cancer growth.

Dosage

• Typical adult dose: 2.5 mg once daily
• Can be taken with or without food
• Take exactly as prescribed by your doctor.

Important Precautions

• Regular medical follow-up and blood tests may be required.
• Do not use during pregnancy; it may harm the unborn baby.
• Use effective contraception during treatment and for at least 3 weeks after the last dose.
• Long-term use may reduce bone density and increase the risk of osteoporosis or fractures.
• May increase cholesterol levels.
• Can cause dizziness, tiredness, or drowsiness; avoid driving or operating machinery until you know how it affects you.

Conditions Requiring Caution

Tell your doctor if you have:

• Osteoporosis or weak bones
• High cholesterol
• Severe liver disease or cirrhosis
• Allergies to medications

Drug & Vaccine Interactions

Certain live vaccines and medications may interact with letrozole. Inform your healthcare provider about all medicines, supplements, and vaccines you are using before starting treatment.

Common Side Effects

• Hot flashes
• Joint, muscle, or bone pain
• Back pain
• Fatigue
• Headache
• Nausea
• Trouble sleeping

Serious Side Effects (Seek Medical Help Immediately)

• Chest pain or signs of heart problems
• Sudden weakness, numbness, or speech problems
• Severe shortness of breath
• Unusual bleeding or bruising
• Yellowing of the skin or eyes
• Severe vision changes
• Bone fractures

Patient Disclaimer

This summary is for educational purposes only and does not replace medical advice, diagnosis, or treatment. Letrozole should only be used under the supervision of a qualified healthcare professional. Do not stop or change your medication without consulting your doctor. Seek immediate medical attention if you experience severe side effects or signs of an allergic reaction.