CYANARO PLUS EYE DROPS ( AZITHROMYCIN + DEXAMETHASONE ) STERILE OPHTHALMIC SOLUTION 5 ML

Cyanaro Plus is a combined antibiotic–corticosteroid formulation used to treat bacterial eye infections associated with inflammation.

Composition

Each 1 mL contains:

• Azithromycin dihydrate equivalent to 10 mg azithromycin (1%)
• Dexamethasone sodium phosphate equivalent to 1 mg dexamethasone
• Benzalkonium chloride (preservative)

Pharmacological Classification

• Azithromycin: Macrolide antibiotic
• Dexamethasone: Corticosteroid (anti-inflammatory)

Mechanism of Action

►Azithromycin

• Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit
• Prevents bacterial growth (bacteriostatic effect)

►Dexamethasone

• Suppresses inflammatory response by:
  • Reducing cytokine release
  • Decreasing capillary permeability
  • Inhibiting immune-mediated tissue damage

Indications

This combination is used for:

• Bacterial conjunctivitis with inflammation
• Blepharitis / blepharoconjunctivitis
• Post-operative ocular inflammation with risk of infection

Azithromycin eye drops alone are indicated for bacterial conjunctivitis and similar infections

Dosage Form & Strength

• Ophthalmic sterile solution
• Strength: Azithromycin 1% + Dexamethasone 0.1%

Pharmacokinetic Features

• High local concentration in ocular tissues
• Minimal systemic absorption with topical use
• Sustained ocular surface contact improves efficacy

Common Side Effects

• Mild eye irritation or burning
• Blurred vision
• Eye redness or discomfort

Serious Risks (Important)

• Increased intraocular pressure (from steroid)
• Cataract formation with prolonged use
• Secondary infections (fungal or viral)
• Hypersensitivity reactions

Precautions

• Avoid prolonged use without medical supervision (due to steroid component)
• Do not wear contact lenses during infection
• Avoid contamination of dropper tip
• Use only for confirmed or suspected bacterial infections

Patient Disclaimer

This information is for educational purposes only and is based on trusted medical sources such as the Mayo Clinic, Cleveland Clinic, and National Institutes of Health.
It is not a substitute for professional medical advice, diagnosis, or treatment. This medication contains a corticosteroid and should only be used under medical supervision. Misuse may lead to serious eye complications. Consult your healthcare provider before use, and seek immediate care if symptoms worsen or severe reactions occur.

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