What it is Dapagliflozin/ Metformin?

• Combination of:
  • Dapagliflozin → removes excess glucose via kidneys
  • Metformin → reduces glucose production and improves insulin use
• Used for type 2 diabetes only (NOT for type 1 diabetes)

Main uses & benefits

• Improves blood sugar control
• Reduces risk of:
  • Heart failure hospitalization
  • Cardiovascular death
• Helps protect against:
  • Chronic kidney disease progression

How to take?

• Usually once daily (morning with food)
• Swallow extended-release tablets whole
• Combine with:
  • Proper diet
  • Exercise
  • Blood sugar monitoring

Who should NOT use / caution

• Do NOT use if:
  • Type 1 diabetes
  • Severe kidney disease
  • Metabolic acidosis or diabetic ketoacidosis
• Use caution in:
  • Elderly patients
  • Kidney, liver, or heart disease
  • Dehydration or infections
• Not established in children <10 years
• Avoid or consult doctor in:
  • Pregnancy & breastfeeding

Major warnings

• Lactic acidosis (serious, from metformin)
  • Symptoms: fatigue, breathing difficulty, stomach pain
• Diabetic ketoacidosis (life-threatening)
• Dehydration & low blood pressure
• Kidney problems
• Urinary tract infections
• Genital yeast infections
• Rare but serious:
  • Fournier’s gangrene

Blood sugar effects

• May cause:
  • Hypoglycemia (especially with insulin/other drugs)
  • Hyperglycemia if dose missed or poor control

Important precautions

• Avoid excess alcohol (↑ risk of lactic acidosis)
• Stop 3 days before surgery or contrast imaging
• Stay well hydrated
• Regular doctor follow-up and lab tests required

Drug interactions

• Many interactions, especially with:
  • Insulin & other antidiabetics
  • Diuretics
  • Certain antibiotics and heart medications
    → Always inform your doctor about all medicines and supplements

Common side effects

• Urinary symptoms (pain, frequent urination)
• Genital itching/discharge
• Nausea, diarrhea
• Dizziness

Serious side effects (urgent care needed)

• Severe infection symptoms
• Trouble breathing
• Swelling/allergic reactions
• Unusual fatigue or confusion

Key advice

• Take exactly as prescribed
• Follow diet + lifestyle plan strictly
• Monitor blood sugar regularly
• Seek medical help if serious symptoms appear

Patient Disclaimer

This medication (Dapagliflozin/Metformin) has been prescribed specifically for your condition. Do not use it without medical supervision.

• Take this medicine exactly as directed by your doctor. Do not change the dose or stop treatment without medical advice.
• This medicine is not suitable for type 1 diabetes or certain serious kidney or metabolic conditions unless advised by your doctor.
• Inform your healthcare provider about all medications, supplements, and medical conditions before starting treatment.
• Follow your recommended diet, exercise plan, and regular blood sugar monitoring to ensure effective treatment.
• Avoid excess alcohol, as it may increase the risk of serious side effects such as lactic acidosis.
• Seek immediate medical attention if you experience symptoms such as severe fatigue, difficulty breathing, persistent nausea or vomiting, abdominal pain, signs of infection, or unusual genital pain or swelling.
• Stay well hydrated, especially during illness, hot weather, or physical activity.
• Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
• This medicine may need to be temporarily stopped before surgery or certain imaging procedures—consult your doctor.
• Keep out of reach of children and store as directed.

This information does not replace professional medical advice. Always consult your doctor or pharmacist for guidance specific to your condition.