Amosar Forte Tablet is used to treat an essential high blood pressure condition in patients who are suffering from the state of uncontrolled blood pressure on losartan or hydrochlorothiazide alone. It is a prescription medicine. Hydrochlorothiazide works by eliminating the excess of water, sodium and potassium salts from the kidney and losartan works by preventing the activity of certain natural substances that tighten the blood vessels which results in decreased blood pressure. Amosar Forte is also used to reduce the risk of stroke and high blood pressure conditions in patients with enlarged heart (left ventricular hypertrophy).

Angiotensin 2 Receptor Blocker

Follow directions on the product label, information guide, and provided by your doctor before using Amosar Forte. Eat this medicine as per your doctor's instructions.

Amosar Forte is eaten with or without food.

The typical adult dose of Amosar Forte is 50 mg/12.5 mg once daily (not more than 100 mg/25 mg once daily). The maximum dose for adults of Amosar Forte is 100/25 mg once daily per day.

Amosar Forte is to be used for longer periods of time. Use of Amosar Forte may be prescribed for the long-term to control the high blood pressure conditions in patients with creatinine clearance less than 30 ml/min.

Tell your doctor if you develop new or worsening symptoms. Talk to your doctor if nausea, pain in the right upper stomach area, yellow eyes or skin, swelling in the feet, ankles, or hands, unexplained weight gain, and inflammation of the connective tissues (systemic lupus erythematosus). Consult with your doctor before stopping the use of Amosar Forte Tablet.

Avoid drinking alcohol with Amosar Forte.

Medicines may be given for uses other than those listed in the medicine guide. Do not use Amosar Forte Tablet for symptoms for which it was not prescribed. Do not give Amosar Forte Tablet to others who may have similar symptoms as you. Self-medication can cause harm.

Store Amosar Forte Tablet at 25°C (77°F), away from moisture, and away from light. Keep this medicine away from children and pets.

Before you use Amosar Forte, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information. Discuss with your doctor if you are allergic to sulfonamide-derived drugs.

Before you use Amosar Forte Tablet, tell your doctor of your medical history including swelling of the face, lips, throat, or tongue, mild to moderate liver problems, bronchial asthma, blood vessel related heart and brain diseases, sulfonamide, aspirin or penicillin allergy, kidney problems, heart attack, enlargement of the heart muscle tissue (left ventricular hypertrophy), difficulty in passing urine (anuria), diabetes, essential high blood pressure, reduce fluid volume in the body (intravascular volume depletion), heart failure, narrowing of the arteries of the kidney (bilateral kidney artery stenosis or stenosis of the artery to a solitary kidney), excessive secretion of aldosterone (primary aldosteronism), absence of lactase (galactose intolerance, the Lapp lactase deficiency), abnormal absorption of glucose and galactose, abnormal quantities of protein in the urine, alcoholic cirrhosis of the liver, stroke, aliskiren, potassium supplements, salt substitutes containing potassium, use of water pills (diuretics), lithium and non-steroidal anti-inflammatory drugs (NSAIDs), low potassium, low sodium or high calcium levels, salt-restricted diet, severe vomiting and/or diarrhea, kidney transplantation, narrowing of the arteries (atherosclerosis), chest pain (angina pectoris), narrowing of the valves of the heart (aortic or mitral valve stenosis), or progressive liver disease. When losartan is used in a patient with alcoholic cirrhosis of the liver, the level of losartan may increase. In patients with liver disease, minor changes of fluid and electrolyte balance may cause liver coma. In patients with asthma or with a history of allergy, allergic reactions may occur. Use of Amosar Forte in patients with diabetes, may cause electrolyte imbalances. Use of losartan in patients with aspirin or penicillin allergy may cause swelling of the lips and eyelids and facial rash. In patients with essential high blood pressure and narrowing of the kidney arteries, this medicine may increase the level of creatinine and urea nitrogen in the blood. Use of Amosar Forte in patients with heart failure and reduced fluid volume in the body (intravascular volume depletion) may cause low blood pressure. Use of Amosar Forte in patients with blood vessel-related heart and brain disease may decrease blood pressure which may result in heart attack or stroke. Use of Amosar Forte in patients with kidney problem may increase the risk of progressive azotemia (abnormally high levels of the nitrogen-containing compound) with kidney failure, electrolyte balance, decreased the production of urine, and possibly fatal. The patients with a history of sulfonamide or penicillin allergy have a risk of developing an eye disease that can cause blindness.

The use of Amosar Forte Tablet may change hemoglobin and hematocrit value. A small decrease in hemoglobin and hematocrit value has been reported in patients while using this medicine.

The use of this medicine may change blood creatinine levels. A minor increase in blood creatinine level has been reported in patients while using this medicine.

The use of Amosar Forte Tablet may change blood urea nitrogen. A minor increase in blood urea nitrogen level has been seen in patients while using this medicine.

The use of this medicine may change bilirubin levels in the blood. Increased levels of bilirubin have been seen in patients while using this medicine.

The use of this medicine may change liver enzymes level. The increase in the level of liver enzymes have been seen in patients while using this medicine.

Amosar Forte Tablet is not safe for use in women who are pregnant. If you are pregnant or planning to become pregnant, you should discuss the impact on the fetus with your doctor before you start using this medicine. Amosar Forte may act directly on the renin-angiotensin system when used during the second and third trimesters of pregnancy. This may cause injury to the developing fetus such as low blood pressure, abnormal brain growth (neonatal skull hypoplasia), nonpassage of urine (anuria), kidney failure, decreased functioning of the kidney, high potassium levels, prematurity, fetal growth restriction (intrauterine growth retardation), heart problem (patent ductus arteriosus), deficiency of amniotic fluid (oligohydramnios) and is possibly fatal to the unborn baby. Thiazides may cross the placenta and this may cause birth defects such as low levels of thrombocytes, jaundice (icterus), electrolyte disturbances and other side effects that occurred in adults. Consult with your doctor on the use of Amosar Forte Tablet during breastfeeding. This medicine is excreted in breast milk and may cause serious side effects in infants. This medicine should not be used during breastfeeding and if the use of Amosar Forte is necessary, the lowest doses should be considered. Consult with your doctor on the use of Amosar Forte Tablet, if you are trying to conceive.

Avoid drinking alcohol with Amosar Forte. Consumption of alcohol may cause low blood pressure while standing up from sitting or lying down.

Amosar Forte can make you feel sleepy. Be careful, especially while driving, while using heavy machinery, or when doing any activity that needs you to be completely alert. The consumption of alcohol with Amosar Forte can worsen the sleepiness. Amosar Forte may cause seizures in some people. Hence, you should discuss with your doctor before performing any activities where a loss of consciousness may cause harm to you or others.

This medicine may increase your sensitivity to sunlight and make you prone to sunburn. If this happens, limit your time outdoors to prevent sunburn. Use a sunscreen and cover your skin when you are outdoors. If you get sunburns on your body, consult with your doctor.

• back pain
• chest pain
• cough
• decrease in the level of hematocrit and haemoglobin
• diarrhea
• dizziness
• fast or irregular heartbeat
• fatigue
• headache
• high blood potassium levels
• indigestion
• inflammation of the pharynx
• inflammation or swelling of the sinuses
• insomnia
• irritation and inflammation of the airways
• kidney failure
• kidney problem
• lack of energy
• leg pain
• low blood sugar
• low blood sugar levels
• mild reduction of haematocrit and haemoglobin
• muscle cramp
• muscle pain
• nausea
• rash
• sinus disorder
• stomach pain
• stuffy nose (nasal congestion)
• upper respiratory infection

• abnormal dreams
• arm